• Biodegradable Sensors for the Brain: Intracranial Pressure Monitor for Traumatic Brain Injury

    Newly developed brain sensors have the capability to biodegrade: that is, all the sensor materials dissolves away in cerebrospinal fluid over a controlled time period. Secondary surgery to remove implants becomes unnecessary and a nidus of infection, bleeding, and surgical risk is removed. The sensors’ wireless operation provides a fully implantable brain monitor in real time, eliminating the need for hospital visits for for additional treatment. The pressure sensors have 3D microelectromechanical systems (MEMS) structure exploiting piezoresistivity of Si nanomembranes, flexibility of biodegradable polymer (PDMS; polydimethylsiloxane), and nano-porous or Mg foil structural materials.

  • Fully Implantable, Wireless Monitoring System with Near-Field Communication (NFC)

    This wireless monitor provides a critically important feature in mobile and real-time monitoring. Here the CPU embedded chip-scale wireless system offers high-speed, digitalized communication with wireless energy and information transfer through near-field electromagnetic coupling of biodegradable metal inductor coils. The miniaturized system is smaller than a dime (U.S. 10-cent coin) and can be implanted in the brain cavity. Various sensor modalities can be integrated with the current NFC system for other types of application such as temperature, pressure, flow rates, pH and glucose sensing and the like.

  • Conformal, Flexible, Implantable Sensors for the Brain

    Soft, flexible and stretchable electronics provide biological conformal contact, delicate measurement and treatment. The demonstration platform in the image shows extremely thin high-performance electronics on the soft substrate offering conformal contact on actual human brain surfaces (from valley to hills). Application of conformal contact electronics ranges from the peripheral nerves, cardiac surface, brain, tumor cells and tissues engineering to wearable and skin-mounted biodevices. Electrophysiological, physical, and chemical sensors can be built in the same manner, and the interfacial structure can be used for other electric stimulators to modulate tissue activity.

  • Biodegradable, Inorganic Platform for High-Performance RF Components

    Inorganic biomaterials provide robust mechanical characteristics and high performance in electronic operation. A clear understanding of the dissolution products and their biocompatibility demonstrates their usability in biomedical devices with degradable features. Studies have demonstrated that we can generate all necessary electronic components − from resistors, diodes, transistors, and capacitors to inductors − with fully biodegradable metal and Si-based semiconductors less than a few micrometer thick, so that all materials can be dissolved away in the body in a few months. Integrating all components lets us provide more complex and advanced electronic circuits for delicate biomedical sensing and treatment.

  • Biomedical Reliability of Electronics Device Implants–Biochemical Degradation and Biocompatibility

    Reliability of implantable medical electronics in biomedicine is critical in patient care. Biomedical reliability considers both electronic devices and biology. The medical device must operate in a controlled-time manner without loss of function or stability, and there are many challenges from mechanical failure, fatigue to biochemical degradation. In addition, biocompatibility is essential for use it in the human body. The images show a very thin Si nanomembrane (< 100 nm) and its degradation in biofluids as well as its compatibility in the cell proliferation test. [The bioresorbable characteristic of Si lets us build fully degradable electronics, but at the same time the electronics must be protected by passive encapsulation to sustain operation. Active encapsulation studies have been made on various types of polymer and inorganic dielectric materials and their combination.]

Notices & News

  • (2019-10) Prof. Kang has been awarded Leading Creative Researchers of 2019 by Seoul National University.

  • (2019-09) Prof. Kang has been awarded the POSCO Cheongam Science Fellowship.

  • (2019-08) BIE had a wrap-up dining to celebrate the end of the summer semester in August 30th.

  • (2019-07) SNU-KIST Joint Research Laboratory opening ceremony was held in 16 July. Department of materials science and engineering professors and KIST researchers attended the ceremony.

  • (2019-06) BIE had a wrap-up seminar for 19 spring semester in 19 June. After the seminar, we got a special dining for celebrating the end of the semester.

  • (2019-04) Sung-Geun gave an oral presentation in biomaterial session, 2019 spring conference of the Korean Institute of Metals and Materials in Changwon, 24 April.

  • (2019-04) BIEL attended 2019 spring conference of the Korean Institute of Metals and Materials in Changwon, 24 April - 26 April.

  • (2019-04) Prof. Kang delivers an invited talk at 2019 MRS Spring Meeting & Exhibit on Biodegradable and Biocompatible Electronics session on “Bioresorbable Electronics for Minimally Invasive Medical Sensing and Treatment of Nervous System”.

  • (2019-04) Prof. Kang delivers an invited talk at SPIE Defense Commercial Sensing on Biodegradable Electronics and Sensor session on “Silicon Transient Electronics: Bioresorbable to Hardware-Secure Device”.

  • (2019-03) Prof. Kang starts a position in Materials Science and Engineering Department at SNU as an assistant professor. We welcome active and passionate students to our group to join our leading research!

  • (2018-12) Wireless Bioresorbable Electronic System for Nonpharmacological Neuroregenerative Therapy, published in Nature Medicine, received wide publicity on YTN, Korea Broadcasting System, and many others.

Welcome to Bio-Interfaced Electronics Laboratory

  • Our philosophy...

    We explore real solutions for healthcare issues in modern society through understanding, exploiting and sharing multidisciplinary science and engineering in bioengineering, biology, materials science, chemistry, mechanics, and electronics engineering. We develop and apply biomedical electronics that provide medical diagnosis and treatment to contribute toward these ultimate goals.

  • Our vision...

    We are entering a new age of personalized and customized biomedical care that requires high-quality and convenient care away from the hospital. This new paradigm urges us to provide the essential engineering keywords “Personal”, “Mobile”, and “Real-time”. Bio-interfaced electronics contributes to the realization of this paradigm in medical instruments and tools.

  • Our research...

    We in the Bio-Interfaced Electronics (BIE) Lab focus on 1. Biodegradable and minimum-invasive implants offering quick, safe medical treatment at complex levels of surgical care, and reducing the need for surgery, 2. Soft and conformal electronics providing interfaces to the human body from skin to organ and allowing carry-on medical electronics, 3. Biomedical device reliability promoting the safe use of recent biomedical devices in terms of time and biomechanical/chemical degradation

We warmly welcome passionate and active students and collaborates who want to lead the new generation of biomedical engineering together.

Current research interested in

  • 01 Biodegradable, minimally invasive implants
  • 02 Soft and conformal biomedical devices
  • 03 Biomedical reliability of electronics